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Difference between Diabetes mellitus and Diabetes insipidus


Point of distinction Diabetes mellitus Diabetes insipidus
Characteristics Hyperglycemia (increased blood sugar level), glycosuria(glucose in urine), polyuria (excessive urine), polydipsia(excessive thirst), polyphagia(excessive appetite) Excretion of large quantity of dilute glucose free urine, polydipsia (excessive thirst) and dehydration
Disease caused due to It is due to deficiency of insulin It is due to failure of secretion of Antidiuretic hormone or vasopressin
Glycourea (excretion of sugar in urine) Sugar is excreted in urine Sugar is not excreted in urine
Blood sugar level Rise or Increased blood glucose level (hyperglycemia) Normal blood glucose level

Increased volume of urine is due to Volume of urine increased due to osmotic effect of glucose Volume of urine increased due to decreased absorption of water in renal tubules
Disorder It is pancreatic disorder It is hypothalamic disorder
Concentration of urine Normal concentration Very dilute urine
Blood cholesterol level Rises Normal
Polyphagia and Hunger Excessive Normal
Ketone bodies in blood and urine Present Absent
Volume of urine Excessive Enormous